It depends on what you want to do. For example you could stick in some conditionals like this in your comprehensions:
# get the squares of each number from 1 to 9, excluding 2
myList = [i**2 for i in range(10) if i != 2]
print(myList)
# --> [0, 1, 9, 16, 25, 36, 49, 64, 81]