I went through this and found all the answers super cool, however wants to add to answer given by @deejers
SELECT
col1,
col2,
col3,
CASE
WHEN condition1 THEN calculation1
WHEN condition2 THEN calculation2
WHEN condition3 THEN calculation3
WHEN condition4 THEN calculation4
WHEN condition5 THEN calculation5
END AS 'calculatedcol1',
col4,
col5 -- etc
FROM table
you can make ELSE optional as its not mandatory, it is very helpful in many scenarios.