I'd highly recommend the Castle DictionaryAdapter, easily one of that project's best-kept secrets. You only need to define an interface with the properties you want, and in one line of code the adapter will generate an implementation, instantiate it, and synchronize its values with a dictionary you pass in. I use it to strongly-type my AppSettings in a web project:
var appSettings =
new DictionaryAdapterFactory().GetAdapter<IAppSettings>(ConfigurationManager.AppSettings);
Note that I did not need to create a class that implements IAppSettings - the adapter does that on the fly. Also, although in this case I'm only reading, in theory if I were setting property values on appSettings, the adapter would keep the underlying dictionary in sync with those changes.