[c#] Hiding a form and showing another when a button is clicked in a Windows Forms application

A) The main GUI thread will run endlessly on the call to Application.Run, so your while loop will never be reached

B) You would never want to have an endless loop like that (the while(true) loop) - it would simply freeze the thread. Not really sure what you're trying to achieve there.

I would create and show the "main" (initial) form in the Main method (as Visual Studio does for you by default). Then in your button handler, create the other form and show it as well as hiding the main form (not closing it). Then, ensure that the main form is shown again when that form is closed via an event. Example:

public partial class Form1 : Form
{
  public Form1()
  {
    InitializeComponent();
  }    

  private void button1_Click(object sender, EventArgs e)
  {      
    Form2 otherForm = new Form2();
    otherForm.FormClosed += new FormClosedEventHandler(otherForm_FormClosed);
    this.Hide();
    otherForm.Show();      
  }

  void otherForm_FormClosed(object sender, FormClosedEventArgs e)
  {
    this.Show();      
  }
}

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