No this is not enough (in some specific cases)! By default PDO uses emulated prepared statements when using MySQL as a database driver. You should always disable emulated prepared statements when using MySQL and PDO:
$dbh->setAttribute(PDO::ATTR_EMULATE_PREPARES, false);
Another thing that always should be done it set the correct encoding of the database:
$dbh = new PDO('mysql:dbname=dbtest;host=127.0.0.1;charset=utf8', 'user', 'pass');
Also see this related question: How can I prevent SQL injection in PHP?
Also note that that only is about the database side of the things you would still have to watch yourself when displaying the data. E.g. by using htmlspecialchars()
again with the correct encoding and quoting style.