All have highlighted almost all major differences between numpy array and python list, I will just brief them out here:
Numpy arrays have a fixed size at creation, unlike python lists (which can grow dynamically). Changing the size of ndarray will create a new array and delete the original.
The elements in a Numpy array are all required to be of the same data type (we can have the heterogeneous type as well but that will not gonna permit you mathematical operations) and thus will be the same size in memory
Numpy arrays are facilitated advances mathematical and other types of operations on large numbers of data. Typically such operations are executed more efficiently and with less code than is possible using pythons build in sequences