man date
on OSX has this example
date -j -f "%a %b %d %T %Z %Y" "`date`" "+%s"
Which I think does what you want.
You can use this for a specific date
date -j -f "%a %b %d %T %Z %Y" "Tue Sep 28 19:35:15 EDT 2010" "+%s"
Or use whatever format you want.