In some cases, it might be a bad idea to first add the column to the DataGridView and then hide it.
I for example have a class that has an NHibernate proxy for an Image property for company logos. If I accessed that property (e.g. by calling its ToString method to show that in a DataGridView), it would download the image from the SQL server. If I had a list of Company objects and used that as the dataSource of the DataGridView like that, then (I suspect) it would download ALL the logos BEFORE I could hide the column.
To prevent this, I used the custom attribute
[System.ComponentModel.Browsable(false)]
on the image property, so that the DataGridView ignores the property (doesn't create the column and doesn't call the ToString methods).
public class Company
{
...
[System.ComponentModel.Browsable(false)]
virtual public MyImageClass Logo { get; set;}