Try:
source `which virtualenvwrapper.sh`
The backticks are command substitution - they take whatever the program prints out and put it in the expression. In this case "which" checks the $PATH to find virtualenvwrapper.sh and outputs the path to it. The script is then read by the shell via 'source'.
If you want this to happen every time you restart your shell, it's probably better to grab the output from the "which" command first, and then put the "source" line in your shell, something like this:
echo "source /path/to/virtualenvwrapper.sh" >> ~/.profile
^ This may differ slightly based on your shell. Also, be careful not to use the a single > as this will truncate your ~/.profile :-o