The answer has been provided a number of times but the the question about when to use each is a design-time decision. I would see it as good practice to try to bundle common method definitions into distinct interfaces and pull them into classes at appropriate abstraction levels. Dumping a common set of abstract and virtual method definitions into a class renders the class unistantiable when it may be best to define a non-abstract class that implements a set of concise interfaces. As always, it depends on what best suits your applications specific needs.