If anyone is looking for a VB.Net answer (as I was initially), here it is:
Public Function IsSatisfied() As Expression(Of Func(Of Charity, String, String, Boolean))
Return Function(charity, name, referenceNumber) (String.IsNullOrWhiteSpace(name) Or
charity.registeredName.ToLower().Contains(name.ToLower()) Or
charity.alias.ToLower().Contains(name.ToLower()) Or
charity.charityId.ToLower().Contains(name.ToLower())) And
(String.IsNullOrEmpty(referenceNumber) Or
charity.charityReference.ToLower().Contains(referenceNumber.ToLower()))
End Function