This can happen when you change the data annotation of a model property. for example: adding [Required] to a property will cause a pending change in the database design.
The safest solution is to run on the Package Manager Console:
add-migration myMirgrationName
which will display the exact changes in the Up() method. Therefore, you can decide if you really want to apply such changes via the:
update-database
Otherwise, you may just delete the latest migration from the __MigrationHistory table and from the Migrations folder the Solution Explorer.