[c#] Formatting text in a TextBlock

You need to use Inlines:

<TextBlock.Inlines>
    <Run FontWeight="Bold" FontSize="14" Text="This is WPF TextBlock Example. " />
    <Run FontStyle="Italic" Foreground="Red" Text="This is red text. " />
</TextBlock.Inlines>

With binding:

<TextBlock.Inlines>
    <Run FontWeight="Bold" FontSize="14" Text="{Binding BoldText}" />
    <Run FontStyle="Italic" Foreground="Red" Text="{Binding ItalicText}" />
</TextBlock.Inlines>

You can also bind the other properties:

<TextBlock.Inlines>
    <Run FontWeight="{Binding Weight}"
         FontSize="{Binding Size}"
         Text="{Binding LineOne}" />
    <Run FontStyle="{Binding Style}"
         Foreground="Binding Colour}"
         Text="{Binding LineTwo}" />
</TextBlock.Inlines>

You can bind through converters if you have bold as a boolean (say).