Just use the *args parameter, which allows you to pass as many arguments as you want after your a,b,c. You would have to add some logic to map args->c,d,e,f but its a "way" of overloading.
def myfunc(a,b, *args, **kwargs):
for ar in args:
print ar
myfunc(a,b,c,d,e,f)
And it will print values of c,d,e,f
Similarly you could use the kwargs argument and then you could name your parameters.
def myfunc(a,b, *args, **kwargs):
c = kwargs.get('c', None)
d = kwargs.get('d', None)
#etc
myfunc(a,b, c='nick', d='dog', ...)
And then kwargs would have a dictionary of all the parameters that are key valued after a,b