You can do it with gridview's datarow bound event. try the following sample of code:
protected void grv_RowDataBound(object sender, GridViewRowEventArgs e)
{
if (e.Row.RowType == DataControlRowType.Header)
{
e.Row.Cells[0].Text = "TiTle";
}
}
For more details about the row databound event study Thsi....