Microsoft recommends to use the "InstallShield Limited Edition for Visual Studio" as replacement for the discontinued "Deployment and Setup Project" - but it is not so nice and nobody else recommends to use it. But for simple setups, and if it is not a problem to relay on commercial third party products, you can use it.
The alternative is to use Windows Installer XML (WiX), but you have to do many things manually that did the Setup-Project by itself.