it was happened to me because I've a strange clash in the namespaces: I had AssemblyA with namespace AssemblyA.ParentNamespace witch defines ClassA and in the same assembly another namespace with name AssemblyA.ParentNamespace.ChildNamespace witch defines a different ClassA (but with the same name)
I had then in AssemblyA.ParentNamespace IInterfaceB witch had a method that in the beginning returns IEnumerable and a ClassB witch implements IInterfaceB
I had later modified the method in ClassB to return IEnumerable but I've forgot to update the IInterfaceB definition, so the method there was still returning IEnumerable the fun fact was that the solution still complile if I did a rebuild all, but the tests witch refers AssemblyA didsn't work and returns the "Metadata file could not be found"error.
updating InterfaceB to correctly return IEnumerable as its implementor ClassB did solved the problem, unfortunately the error message was vague and also the fact that the compilation worked makes me suppose that maybe there is something to fix in the compiler