To make a Base64 encoded String URL friendly, in JavaScript you could do something like this:
// if this is your Base64 encoded string
var str = 'VGhpcyBpcyBhbiBhd2Vzb21lIHNjcmlwdA==';
// make URL friendly:
str = str.replace(/\+/g, '-').replace(/\//g, '_').replace(/\=+$/, '');
// reverse to original encoding
str = (str + '===').slice(0, str.length + (str.length % 4));
str = str.replace(/-/g, '+').replace(/_/g, '/');
See also this Fiddle: http://jsfiddle.net/magikMaker/7bjaT/