If you are using MariaDB or MySQL 8.0, they have a function
REGEXP_REPLACE(col, regexp, replace)
See MariaDB docs and PCRE Regular expression enhancements
Note that you can use regexp grouping as well (I found that very useful):
SELECT REGEXP_REPLACE("stackoverflow", "(stack)(over)(flow)", '\\2 - \\1 - \\3')
returns
over - stack - flow