I agree with the marked answer by Drew Hall. The answer could use some additional notes though.
For the vast majority of software developers the processor and compiler are no longer relevant to the question. Most of us are far beyond the 8088 and MS-DOS. It is perhaps only relevant for those who are still developing for embedded processors...
At my software company Math (add/sub/mul/div) should be used for all mathematics. While Shift should be used when converting between data types eg. ushort to byte as n>>8 and not n/256.