One of the easy ways is not to store the output in a variable, but directly iterate over it with a while/read loop.
Something like:
grep xyz abc.txt | while read -r line ; do
echo "Processing $line"
# your code goes here
done
There are variations on this scheme depending on exactly what you're after.
If you need to change variables inside the loop (and have that change be visible outside of it), you can use process substitution as stated in fedorqui's answer:
while read -r line ; do
echo "Processing $line"
# your code goes here
done < <(grep xyz abc.txt)