[python] How to write to an existing excel file without overwriting data (using pandas)?

Old question, but I am guessing some people still search for this - so...

I find this method nice because all worksheets are loaded into a dictionary of sheet name and dataframe pairs, created by pandas with the sheetname=None option. It is simple to add, delete or modify worksheets between reading the spreadsheet into the dict format and writing it back from the dict. For me the xlsxwriter works better than openpyxl for this particular task in terms of speed and format.

Note: future versions of pandas (0.21.0+) will change the "sheetname" parameter to "sheet_name".

# read a single or multi-sheet excel file
# (returns dict of sheetname(s), dataframe(s))
ws_dict = pd.read_excel(excel_file_path,
                        sheetname=None)

# all worksheets are accessible as dataframes.

# easy to change a worksheet as a dataframe:
mod_df = ws_dict['existing_worksheet']

# do work on mod_df...then reassign
ws_dict['existing_worksheet'] = mod_df

# add a dataframe to the workbook as a new worksheet with
# ws name, df as dict key, value:
ws_dict['new_worksheet'] = some_other_dataframe

# when done, write dictionary back to excel...
# xlsxwriter honors datetime and date formats
# (only included as example)...
with pd.ExcelWriter(excel_file_path,
                    engine='xlsxwriter',
                    datetime_format='yyyy-mm-dd',
                    date_format='yyyy-mm-dd') as writer:

    for ws_name, df_sheet in ws_dict.items():
        df_sheet.to_excel(writer, sheet_name=ws_name)

For the example in the 2013 question:

ws_dict = pd.read_excel('Masterfile.xlsx',
                        sheetname=None)

ws_dict['Main'] = data_filtered[['Diff1', 'Diff2']]

with pd.ExcelWriter('Masterfile.xlsx',
                    engine='xlsxwriter') as writer:

    for ws_name, df_sheet in ws_dict.items():
        df_sheet.to_excel(writer, sheet_name=ws_name)

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