[python] Pandas/Python: Set value of one column based on value in another column

You can use pandas.DataFrame.mask to add virtually as many conditions as you need:

data = {'a': [1,2,3,4,5], 'b': [6,8,9,10,11]}

d = pd.DataFrame.from_dict(data, orient='columns')
c = {'c1': (2, 'Value1'), 'c2': (3, 'Value2'), 'c3': (5, d['b'])}

d['new'] = np.nan
for value in c.values():
    d['new'].mask(d['a'] == value[0], value[1], inplace=True)

d['new'] = d['new'].fillna('Else')
d

Output:

    a   b   new
0   1   6   Else
1   2   8   Value1
2   3   9   Value2
3   4   10  Else
4   5   11  11

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