I think the biggest mistakes that all developers and DBAs do is believing too much on conventions. What I mean by that is that convention are only guide lines that for most cases will work but not necessarily always. I great example is normalization and foreign keys, I know most people wont like this, but normalization can cause complexity and cause loss of performance as well, so if there is no reason to move a phone number to a phones table, don't do it. On the foreign keys, they are great for most cases, but if you are trying to create something that can work by it self when needed the foreign key will be a problem in the future, and also you loose performance. Anyways, as I sad rules and conventions are there to guide, and they should always be though of but not necessarily implemented, analysis of each case is what should always be done.