[python] Python if not == vs if !=

An additional note, since the other answers answered your question mostly correctly, is that if a class only defines __eq__() and not __ne__(), then your COMPARE_OP (!=) will run __eq__() and negate it. At that time, your third option is likely to be a tiny bit more efficient, but should only be considered if you NEED the speed, since it's difficult to understand quickly.

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