Full admin rights for the whole server, or a specific database? I think the others answered for a database, but for the server:
USE [master];
GO
CREATE LOGIN MyNewAdminUser
WITH PASSWORD = N'abcd',
CHECK_POLICY = OFF,
CHECK_EXPIRATION = OFF;
GO
EXEC sp_addsrvrolemember
@loginame = N'MyNewAdminUser',
@rolename = N'sysadmin';
You may need to leave off the CHECK_ parameters depending on what version of SQL Server Express you are using (it is almost always useful to include this information in your question).