sed -i '/pattern/d' file
Use 'd' to delete a line. This works at least with GNU-Sed.
If your Sed doesn't have the option, to change a file in place, maybe you can use an intermediate file, to store the modification:
sed '/pattern/d' file > tmpfile && mv tmpfile file
Writing directly to the source usually doesn't work: sed '/pattern/d' file > file
so make a copy before trying out, if you doubt it.