iframe is also vulnerable to Cross Frame Scripting:
I'm assuming cross-domain iFrame since presumably the risk would be lower if you controlled it yourself.
"Dangerous" and "Security risk" are not the first things that spring to mind when people mention iframes … but they can be used in clickjacking attacks.
The IFRAME element may be a security risk if your site is embedded inside an IFRAME on hostile site. Google "clickjacking" for more details. Note that it does not matter if you use <iframe> or not. The only real protection from this attack is to add HTTP header X-Frame-Options: DENY and hope that the browser knows its job.
In addition, IFRAME element may be a security risk if any page on your site contains an XSS vulnerability which can be exploited. In that case the attacker can expand the XSS attack to any page within the same domain that can be persuaded to load within an <iframe> on the page with XSS vulnerability. This is because content from the same origin (same domain) is allowed to access the parent content DOM (practically execute JavaScript in the "host" document). The only real protection methods from this attack is to add HTTP header X-Frame-Options: DENY and/or always correctly encode all user submitted data (that is, never have an XSS vulnerability on your site - easier said than done).
That's the technical side of the issue. In addition, there's the issue of user interface. If you teach your users to trust that URL bar is supposed to not change when they click links (e.g. your site uses a big iframe with all the actual content), then the users will not notice anything in the future either in case of actual security vulnerability. For example, you could have an XSS vulnerability within your site that allows the attacker to load content from hostile source within your iframe. Nobody could tell the difference because the URL bar still looks identical to previous behavior (never changes) and the content "looks" valid even though it's from hostile domain requesting user credentials.
If somebody claims that using an <iframe> element on your site is dangerous and causes a security risk, he does not understand what <iframe> element does, or he is speaking about possibility of <iframe> related vulnerabilities in browsers. Security of <iframe src="..."> tag is equal to <img src="..." or <a href="..."> as long there are no vulnerabilities in the browser. And if there's a suitable vulnerability, it might be possible to trigger it even without using <iframe>, <img> or <a> element, so it's not worth considering for this issue.
However, be warned that content from <iframe> can initiate top level navigation by default. That is, content within the <iframe> is allowed to automatically open a link over current page location (the new location will be visible in the address bar). The only way to avoid that is to add sandbox attribute without value allow-top-navigation. For example, <iframe sandbox="allow-forms allow-scripts" ...>. Unfortunately, sandbox also disables all plugins, always. For example, Youtube content cannot be sandboxed because Flash player is still required to view all Youtube content. No browser supports using plugins and disallowing top level navigation at the same time.
Note that X-Frame-Options: DENY also protects from rendering performance side-channel attack that can read content cross-origin (also known as "Pixel perfect Timing Attacks").
Source: Stackoverflow.com