echo '\x12\x02'
will not be interpreted, and will literally write the string \x12\x02
(and append a newline) to the specified serial port. Instead use
echo -n ^R^B
which you can construct on the command line by typing CtrlVCtrlR and CtrlVCtrlB. Or it is easier to use an editor to type into a script file.
The stty
command should work, unless another program is interfering. A common culprit is gpsd
which looks for GPS devices being plugged in.