In my case I'd forgotten the open and close parantheses at the end of the definition of the function wrapping all of my code in the exported module. I.e. I had:
(function () {
'use strict';
module.exports.MyClass = class{
...
);
Instead of:
(function () {
'use strict';
module.exports.MyClass = class{
...
)();
The compiler doesn't complain, but the require statement in the importing module doesn't set the variable it's being assigned to, so it's undefined at the point you try to construct it and it will give the TypeError: MyClass is not a constructor
error.