If the OK line is the first line and the last line is the dot you could consider slice them off like this:
TestString = '''OK SYS 10 LEN 20 12 43
1233a.fdads.txt,23 /data/a11134/a.txt
3232b.ddsss.txt,32 /data/d13f11/b.txt
3452d.dsasa.txt,1234 /data/c13af4/f.txt
.
'''
print('\n'.join(TestString.split()[1:-1]))
However if this is a very large string you may run into memory problems.