Demo:
In [255]: df = pd.DataFrame(np.random.rand(5, 6), columns=list('abcdef'))
In [256]: df
Out[256]:
a b c d e f
0 0.823638 0.767999 0.460358 0.034578 0.592420 0.776803
1 0.344320 0.754412 0.274944 0.545039 0.031752 0.784564
2 0.238826 0.610893 0.861127 0.189441 0.294646 0.557034
3 0.478562 0.571750 0.116209 0.534039 0.869545 0.855520
4 0.130601 0.678583 0.157052 0.899672 0.093976 0.268974
In [257]: dfs = np.split(df, [4], axis=1)
In [258]: dfs[0]
Out[258]:
a b c d
0 0.823638 0.767999 0.460358 0.034578
1 0.344320 0.754412 0.274944 0.545039
2 0.238826 0.610893 0.861127 0.189441
3 0.478562 0.571750 0.116209 0.534039
4 0.130601 0.678583 0.157052 0.899672
In [259]: dfs[1]
Out[259]:
e f
0 0.592420 0.776803
1 0.031752 0.784564
2 0.294646 0.557034
3 0.869545 0.855520
4 0.093976 0.268974
np.split() is pretty flexible - let's split an original DF into 3 DFs at columns with indexes [2,3]:
In [260]: dfs = np.split(df, [2,3], axis=1)
In [261]: dfs[0]
Out[261]:
a b
0 0.823638 0.767999
1 0.344320 0.754412
2 0.238826 0.610893
3 0.478562 0.571750
4 0.130601 0.678583
In [262]: dfs[1]
Out[262]:
c
0 0.460358
1 0.274944
2 0.861127
3 0.116209
4 0.157052
In [263]: dfs[2]
Out[263]:
d e f
0 0.034578 0.592420 0.776803
1 0.545039 0.031752 0.784564
2 0.189441 0.294646 0.557034
3 0.534039 0.869545 0.855520
4 0.899672 0.093976 0.268974