Try this:
jQuery('#main').css('opacity', '0.6');
or
jQuery('#main').css({'filter':'alpha(opacity=60)', 'zoom':'1', 'opacity':'0.6'});
if you want to support IE7, IE8 and so on.
try using .animate instead of .css or even just on the opacity one and leave .css on the display?? may b
jQuery(document).ready(function(){
if (jQuery('#nav .drop').animate('display') === 'block') {
jQuery('#main').animate('opacity') = '0.6';
Try with this :
jQuery('#main').css({ opacity: 0.6 });
Source: Stackoverflow.com