I like the ndiff answer, but if you want to spit it all into a list of only the changes, you could do something like:
import difflib
case_a = 'afrykbnerskojezyczny'
case_b = 'afrykanerskojezycznym'
output_list = [li for li in difflib.ndiff(case_a, case_b) if li[0] != ' ']