How about skipping the particular file while iterating over all the files in the folder! Below code would skip all excel files that start with 'eph'
import glob
import re
for file in glob.glob('*.xlsx'):
if re.match('eph.*\.xlsx',file):
continue
else:
#do your stuff here
print(file)
This way you can use more complex regex patterns to include/exclude a particular set of files in a folder.