[node.js] Failed to connect to 127.0.0.1:27017, reason: errno:111 Connection refused

Issue was with the connection to the database, it could be due to several reasons. For me it was low disk space on my server machine, and when mongo tries to connect it refuse because of low disk, check your server machine local storage with du -sh if you have low storage space, check your logs size and take step accordingly, issue may exist because of dbpath contradict in /etc/mongod.conf and server actually running dbpath with mongod If you are facing such type of issue, please check my answer in the given link below. https://stackoverflow.com/a/53057695/8247133

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