If all objects in your array are unique or you want to remove all occurrences of an object when found, you could fast enumerate on an array copy and use [NSMutableArray removeObject:] to remove the object from the original.
NSMutableArray *myArray;
NSArray *myArrayCopy = [NSArray arrayWithArray:myArray];
for (NSObject *anObject in myArrayCopy) {
if (shouldRemove(anObject)) {
[myArray removeObject:anObject];
}
}