An UpdatePanel completely replaces the contents of the update panel on an update. This means that those events you subscribed to are no longer subscribed because there are new elements in that update panel.
What I've done to work around this is re-subscribe to the events I need after every update. I use $(document).ready() for the initial load, then use Microsoft's PageRequestManager (available if you have an update panel on your page) to re-subscribe every update.
$(document).ready(function() {
// bind your jQuery events here initially
});
var prm = Sys.WebForms.PageRequestManager.getInstance();
prm.add_endRequest(function() {
// re-bind your jQuery events here
});
The PageRequestManager is a javascript object which is automatically available if an update panel is on the page. You shouldn't need to do anything other than the code above in order to use it as long as the UpdatePanel is on the page.
If you need more detailed control, this event passes arguments similar to how .NET events are passed arguments (sender, eventArgs) so you can see what raised the event and only re-bind if needed.
Here is the latest version of the documentation from Microsoft: msdn.microsoft.com/.../bb383810.aspx
A better option you may have, depending on your needs, is to use jQuery's .on(). These method are more efficient than re-subscribing to DOM elements on every update. Read all of the documentation before you use this approach however, since it may or may not meet your needs. There are a lot of jQuery plugins that would be unreasonable to refactor to use .delegate() or .on(), so in those cases, you're better off re-subscribing.