Cast the datetime to a date, then GROUP BY using this syntax:
SELECT SUM(foo), DATE(mydate) FROM a_table GROUP BY DATE(a_table.mydate);
Or you can GROUP BY the alias as @orlandu63 suggested:
SELECT SUM(foo), DATE(mydate) DateOnly FROM a_table GROUP BY DateOnly;
Though I don't think it'll make any difference to performance, it is a little clearer.