Don't use wsgiref for production. Use Apache and mod_wsgi, or something else.
We continue to see these connection resets, sometimes frequently, with wsgiref (the backend used by the werkzeug test server, and possibly others like the Django test server). Our solution was to log the error, retry the call in a loop, and give up after ten failures. httplib2 tries twice, but we needed a few more. They seem to come in bunches as well - adding a 1 second sleep might clear the issue.
We've never seen a connection reset when running through Apache and mod_wsgi. I don't know what they do differently, (maybe they just mask them), but they don't appear.
When we asked the local dev community for help, someone confirmed that they see a lot of connection resets with wsgiref that go away on the production server. There's a bug there, but it is going to be hard to find it.