[javascript] How can I execute a python script from an html button?

I've done exactly this on Windows. I have a local .html page that I use as a "dashboard" for all my current work. In addition to the usual links, I've been able to add clickable links that open MS-Word documents, Excel spreadsheets, open my IDE, ssh to servers, etc. It is a little involved but here's how I did it ...

First, update the Windows registry. Your browser handles usual protocols like http, https, ftp. You can define your own protocol and a handler to be invoked when a link of that protocol-type is clicked. Here's the config (run with regedit)

[HKEY_CLASSES_ROOT\mydb]
@="URL:MyDB Document"
"URL Protocol"=""

[HKEY_CLASSES_ROOT\mydb\shell]
@="open"

[HKEY_CLASSES_ROOT\mydb\shell\open]

[HKEY_CLASSES_ROOT\mydb\shell\open\command]
@="wscript C:\_opt\Dashboard\Dashboard.vbs \"%1\""

With this, when I have a link like <a href="mydb:open:ProjectX.docx">ProjectX</a>, clicking it will invoke C:\_opt\Dashboard\Dashboard.vbs passing it the command line parameter open:ProjectX.docx. My VBS code looks at this parameter and does the necessary thing (in this case, because it ends in .docx, it invokes MS-Word with ProjectX.docx as the parameter to it.

Now, I've written my handler in VBS only because it is very old code (like 15+ years). I haven't tried it, but you might be able to write a Python handler, Dashboard.py, instead. I'll leave it up to you to write your own handler. For your scripts, your link could be href="mydb:runpy:whatever.py" (the runpy: prefix tells your handle to run with Python).

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