I've just installed Anaconda on Windows 10 and have been trying to configure Jupyter to open in my specified directory, including updating the Jupyter config file as suggested above. This didn't work. After viewing other threads, I stumbled on file "notebook.bat" in the .anaconda\scripts\ folder. This launches Jupyter. I took a copy of the .bat file into the folder I want to work in, ran it, and voila - Jupyter launches in that folder and I no longer see every folder on my PC, just the one I want. One desktop shortcut later and I'm a happy 'non-techy'. I hope this helps.