Assuming you don't have extraneous whitespace:
with open('file') as f:
w, h = [int(x) for x in next(f).split()] # read first line
array = []
for line in f: # read rest of lines
array.append([int(x) for x in line.split()])
You could condense the last for loop into a nested list comprehension:
with open('file') as f:
w, h = [int(x) for x in next(f).split()]
array = [[int(x) for x in line.split()] for line in f]