Result is shown in the following code as column number (8,9 etc.):
Dim lastColumn As Long
lastColumn = Sheet1.Cells(1, Columns.Count).End(xlToLeft).Column
MsgBox lastColumn
Result is shown in the following code as letter (H,I etc.):
Dim lastColumn As Long
lastColumn = Sheet1.Cells(1, Columns.Count).End(xlToLeft).Column
MsgBox Split(Sheet1.Cells(1, lastColumn).Address, "$")(1)