The following jQuery selects div nodes that contain text but have no children, which are the leaf nodes of the DOM tree.
$('div:contains("test"):not(:has(*))').css('background-color', 'red');
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<div>div1_x000D_
<div>This is a test, nested in div1</div>_x000D_
<div>Nested in div1<div>_x000D_
</div>_x000D_
<div>div2 test_x000D_
<div>This is another test, nested in div2</div>_x000D_
<div>Nested in div2</div>_x000D_
</div>_x000D_
<div>_x000D_
div3_x000D_
</div>_x000D_
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<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/1.12.4/jquery.min.js"></script>
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