You can use the null coalescing double question marks to test for nulls in a string or other nullable value type:
textBox1.Text = s ?? "Is null";
The operator '??' asks if the value of 's' is null and if not it returns 's'; if it is null it returns the value on the right of the operator.
More info here: https://msdn.microsoft.com/en-us/library/ms173224.aspx
And also worth noting there's a null-conditional operator ?. and ?[ introduced in C# 6.0 (and VB) in VS2015
textBox1.Text = customer?.orders?[0].description ?? "n/a";
This returns "n/a" if description is null, or if the order is null, or if the customer is null, else it returns the value of description.
More info here: https://msdn.microsoft.com/en-us/library/dn986595.aspx