[python] how to create a list of lists

First of all do not use list as a variable name- that is a builtin function.

I'm not super clear of what you're asking (a little more context would help), but maybe this is helpful-

my_list = []
my_list.append(np.genfromtxt('temp.txt', usecols=3, dtype=[('floatname','float')], skip_header=1))
my_list.append(np.genfromtxt('temp2.txt', usecols=3, dtype=[('floatname','float')], skip_header=1))

That will create a list (a type of mutable array in python) called my_list with the output of the np.getfromtext() method in the first 2 indexes.

The first can be referenced with my_list[0] and the second with my_list[1]