You could use label based using .loc or index based using .iloc method to do column-slicing including column ranges:
In [50]: import pandas as pd
In [51]: import numpy as np
In [52]: df = pd.DataFrame(np.random.rand(4,4), columns = list('abcd'))
In [53]: df
Out[53]:
a b c d
0 0.806811 0.187630 0.978159 0.317261
1 0.738792 0.862661 0.580592 0.010177
2 0.224633 0.342579 0.214512 0.375147
3 0.875262 0.151867 0.071244 0.893735
In [54]: df.loc[:, ["a", "b", "d"]] ### Selective columns based slicing
Out[54]:
a b d
0 0.806811 0.187630 0.317261
1 0.738792 0.862661 0.010177
2 0.224633 0.342579 0.375147
3 0.875262 0.151867 0.893735
In [55]: df.loc[:, "a":"c"] ### Selective label based column ranges slicing
Out[55]:
a b c
0 0.806811 0.187630 0.978159
1 0.738792 0.862661 0.580592
2 0.224633 0.342579 0.214512
3 0.875262 0.151867 0.071244
In [56]: df.iloc[:, 0:3] ### Selective index based column ranges slicing
Out[56]:
a b c
0 0.806811 0.187630 0.978159
1 0.738792 0.862661 0.580592
2 0.224633 0.342579 0.214512
3 0.875262 0.151867 0.071244