I had to get rid of the NULL values before using the command recommended by Andy above. An example:
df = pd.DataFrame(index = [0, 1, 2], columns=['first', 'second', 'third'])
df.ix[:, 'first'] = 'myword'
df.ix[0, 'second'] = 'myword'
df.ix[2, 'second'] = 'myword'
df.ix[1, 'third'] = 'myword'
df
first second third
0 myword myword NaN
1 myword NaN myword
2 myword myword NaN
Now running the command:
~df["second"].str.contains(word)
I get the following error:
TypeError: bad operand type for unary ~: 'float'
I got rid of the NULL values using dropna() or fillna() first and retried the command with no problem.