You can use boolean mask on the dtypes attribute:
In [11]: df = pd.DataFrame([[1, 2.3456, 'c']])
In [12]: df.dtypes
Out[12]:
0 int64
1 float64
2 object
dtype: object
In [13]: msk = df.dtypes == np.float64 # or object, etc.
In [14]: msk
Out[14]:
0 False
1 True
2 False
dtype: bool
You can look at just those columns with the desired dtype:
In [15]: df.loc[:, msk]
Out[15]:
1
0 2.3456
Now you can use round (or whatever) and assign it back:
In [16]: np.round(df.loc[:, msk], 2)
Out[16]:
1
0 2.35
In [17]: df.loc[:, msk] = np.round(df.loc[:, msk], 2)
In [18]: df
Out[18]:
0 1 2
0 1 2.35 c